Cooking A Turkey On 250. To cook turkey overnight at 225 degrees you need to first cook it at 450 degrees for 45 minutes and then reduce the oven temperature and set your alarm. In a 250 degree oven you get less of that phenomenon.
An instant read thermometer inserted into the thickest part of the thigh near the bone should read 180 degrees f 82 degrees c. It seems strange but you can cook the turkey to temperatures that by intuition should result in a dessicated horrible bird think 200 degrees internal and instead end up with a bird that s moister than a bird cooked to 160 using the normal methods. If you really want to cut down the stress of cooking a big thanksgiving or christmas dinner you might want to consider slow cooking your turkey.
Be sure you cook the turkey long enough and that you have plenty of time to have the turkey rest so the juices absorb into the meat as it cools.
The bigger the bird the worse the effect. Bake turkey uncovered in the preheated oven until no longer pink at the bone and the juices run clear about 3 hours. Tips for a perfect bird. The bigger the bird the worse the effect.